🤓For those who love to geek out on research like we do—welcome back! And if you’re new here, we occasionally share some of the latest studies that impact health and performance, along with our quick takes. These insights can help you make more informed choices about your nutrition and overall health. Let’s dive in!
Are Dietary Supplements Regulated?
📖 Common questions and misconceptions about dietary supplements and the industry—what does science and the law really say?
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Nutrify Notes: We love the ISSN papers that tackle persistent myths—this time around supplements—from “they’re unregulated” to “natural means safe.” This is an important read for anyone who takes a supplement (which, according to prevalence statistics = most of you).
Takeaways: Supplement claims aren’t always what they seem. The bottom line? Informed supplement consumers ask questions, read labels, favor third-party testing, and seek professional guidance to build a safe and effective supplement plan based on actual needs.
How Low Carbohydrate Intake May Influence REDs Risk
📖 Low Energy Availability, Carbohydrate Intake, and Relative Energy Deficiency in Sport: The Low Triiodothyronine Hypothesis
🔗 Read the article
Nutrify Notes: This paper presents a hypothesis of how low carbohydrate availability (LCA), especially in combination with problematic low energy availability (LEA), may suppress triiodothyronine (T3) levels. Low T3 has been identified as one of the primary diagnostic markers for Relative Energy Deficiency in Sport (REDs), given its role in influencing other hormones like insulin, leptin, estradiol, IGF-1, and growth hormone.
Takeaways: If you’re training hard but underfueling carbs—even with enough total calories—T3 may drop, increasing your risk of developing REDs. This highlights the importance of assessing your overall energy intake and the macronutrient distribution to ensure you’re fueling your body in a way that supports both performance and overall health.
New REDs Mouse Model Offers Insights on How REDs May Disrupt Multiple Systems
📖 Multi Organ Transcriptome Atlas of a Mouse Model of Relative Energy Deficiency in Sport
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Nutrify Notes: This study was presented last month at the 2025 Female Athlete Conference, where researchers shared findings from a new mouse model designed to mimic Relative Energy Deficiency in Sport (REDs). By restricting energy intake relative to exercise, they observed system-wide effects across multiple organs and identified sex-specific differences in responses. They also identified gene expression changes and potential blood-based biomarkers that could eventually support earlier identification of REDs in humans.
Takeaways: Despite the debates about the relevance of mouse studies, this important work offers new clues that could help guide the development of future diagnostic tools and treatment strategies for REDs in humans Additionally, these findings further reinforce the importance of eating enough to meet the demands of your training—not just to fuel performance, but to protect long-term health.
If you’re ready to fuel your body smarter and ensure your nutrition supports both your performance and long-term health, it might be time for a personalized nutrition assessment. A clear, personalized plan, paired with ongoing coaching support, can make all the difference when it comes to preventing risks like REDs and optimizing your health and performance. Schedule a complimentary information call today to learn more & get started!
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